Ten-year experience retrospective in investigation of the frequency of sex chromosome aneuploidies diagnosed in a reference medical center in Türkiye

Background: Sex chromosome aneuploidies (SCAs) are characterized by the gain or loss of entire parts sex chromosomes.Methods: In 5212 cases studied over last 10 years in Medical Genetics Department, we found 3793 (72.78%) other chromosomal establishments and 1419 (27.22%) using retrospective archive-file scanning method.Results: 839 (31.32%) with anomalies were female, 580 (22.8%) male. While Triple X-Super Female Syndrome 423 (15.8%) is most common women, Klinefelter 508 (20.0%) men. Among sent to our outpatient clinic for various indications (prediagnosis) karyotype analysis, 1447 (54.0%) women 1193 (47.1%) men a prediagnosis habitual abortion; followed 298 (11.1%) infertility 350 (13.8%) 167 (6.6%) people preliminary diagnosis azoospermia men, it was determined be 124 (4.6%) primary amenorrhea. analysis made according diagnosis, 1839 (68.7%) 1954 (77.1%) normal. important syndrome first Turner 315 (11.8%) while Jacob’s (47, XYY) detected 13 (0.5%) men.Conclusions: As result, evaluation 10-year cytogenetic analyses these case groups contributes creation regional data.